Publications

Treatment of a patient with severe systemic sclerosis (SSc) using CD19-targeted CAR T cells.

Bergmann C, Müller F, Distler JHW, Györfi AH, Völkl S, Aigner M, Kretschmann S, Reimann H, Harrer T, Bayerl N, Boeltz S, Wirsching A, Taubmann J, Rösler W, Spriewald B, Wacker J, Atzinger A, Uder M, Kuwert T, Mackensen A, Schett G.

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Author Correction: DeepNAPSI multi-reader nail psoriasis prediction using deep learning.

Stunning of neutrophils accounts for the anti-inflammatory effects of clodronate liposomes

Culemann S, Knab K, Euler M, Wegner A, Garibagaoglu H, Ackermann J, Fischer K, Kienhöfer D, Crainiciuc G, Hahn J, Grüneboom A, Nimmerjahn F, Uderhardt S, Hidalgo A, Schett G, Hoffmann MH, Krönke G.

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Current and Emerging Targeted Therapies for Ulcerative Colitis.

Pietschner R, Rath T, Neurath MF, Atreya R.

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Physical Function of RA patients Tapering Treatment-A Post Hoc Analysis of the Randomized Controlled RETRO Trial.

Stephan M, Tascilar K, Yalcin-Mutlu M, Hagen M, Haschka J, Reiser M, Hartmann F, Kleyer A, Hueber AJ, Manger B, Figueiredo C, Cobra JF, Tony HP, Finzel S, Kleinert S, Wendler J, Schuch F, Ronneberger M, Feuchtenberger M, Fleck M, Manger K, Ochs W, Schmitt-Haendle M, Lorenz HM, Nüsslein H, Alten R, Henes J, Krüger K, Schett G, Rech J.

Interleukin 36 receptor-inducible matrix metalloproteinase 13 mediates intestinal fibrosis.

Rationale, current state and opportunities in combining biologic disease modifying antirheumatic drugs in rheumatoid and psoriatic arthritis.

Mutlu MY, Tascilar K, Schett G.

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Rapid single-cell physical phenotyping of mechanically dissociated tissue biopsies.

Soteriou D, Kubánková M, Schweitzer C, López-Posadas R, Pradhan R, Thoma OM, Györfi AH, Matei AE, Waldner M, Distler JHW, Scheuermann S, Langejürgen J, Eckstein M, Schneider-Stock R, Atreya R, Neurath MF, Hartmann A, Guck J.

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Genetic underpinnings of the psoriatic spectrum.

Klima J, Deen Hayatu M, Hüffmeier U.*

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Th2-dependent STAT6-regulated genes in intestinal epithelial cells mediate larval trapping during secondary Heligmosomoides polygyrus bakeri infection.

Westermann S, Schubart C, Dietschmann A, Castiglione K, Radtke D, Voehringer D.

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Moonlighting chromatin: when DNA escapes nuclear control.

Singh J, Boettcher M, Dölling M, Heuer A, Hohberger B, Leppkes M, Naschberger E, Schapher M, Schauer C, Schoen J, Stürzl M, Vitkov L, Wang H, Zlatar L, Schett GA, Pisetsky DS, Liu ML, Herrmann M, Knopf J.

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Granulocyte development, tissue recruitment, and function during allergic inflammation.

Radtke D, Voehringer D.

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Analysis of Hand Joint Space Morphology in Women and Men with Hereditary Hemochromatosis.

Heilmeier U, Burghardt AJ, Tse JJ, Kapoor P, Stok KS, Manske S, Voll RE, Schett G, Finzel S.

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Tissue-specific macrophages: how they develop and choreograph tissue biology.

Mass E, Nimmerjahn F, Kierdorf K, Schlitzer A.

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Pivotal Role of Intestinal Microbiota and Intraluminal Metabolites for the Maintenance of Gut-Bone Physiology

Grüner N, Ortlepp AL, Mattner J.

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CD83 acts as immediate early response gene in activated macrophages and exhibits specific intracellular trafficking properties.

Langguth P, Peckert-Maier K, Beck P, Kuhnt C, Draßner C, Deinzer A, Steinkasserer A, Wild AB

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Expression and function of α4β7 integrin predict the success of vedolizumab treatment in inflammatory bowel disease.

Schneider I, Allner C, Mühl L, Melde M, Lissner D, Mantzivi E, Glauben R, Vitali F, Becker E, Atreya I, Müller TM, Atreya R, Siegmund B, Neurath MF, Zundler S.

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Breaking the Gingival Barrier in Periodontitis

Vitkov L, Singh J, Schauer C, Minnich B, Krunić J, Oberthaler H, Gamsjaeger S, Herrmann M, Knopf J, Hannig M.

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IL-4 and helminth infection downregulate MINCLE-dependent macrophage response to mycobacteria and Th17 adjuvanticity.

Schick J, Altunay M, Lacorcia M, Marschner N, Westermann S, Schluckebier J, Schubart C, Bodendorfer B, Christensen D, Alexander C, Wirtz S, Voehringer D, da Costa CP, Lang R.

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Identification of circulating microRNA patterns in patients in psoriasis and psoriatic arthritis.

Haschka J, Simon D, Bayat S, Messner Z, Kampylafka E, Fagni F, Skalicky S, Hackl M, Resch H, Zwerina J, Kleyer A, Cavallaro A, Sticherling M, Schett G, Kocijan R, Rech J.

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Circumventing pyroptosis via hyperactivation shapes superior immune responses of human type 2 dendritic cells compared to type 3 dendritic cells.

Hatscher L, Kaszubowski T, Amon L, Dudziak D, Heger L.

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Bovine blood derived macrophages are unable to control Coxiella burnetii replication under hypoxic conditions.

Mauermeir M, Ölke M, Hayek I, Schulze-Luehrmann J, Dettmer K, Oefner PJ, Berens C, Menge C, Lührmann A.

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Contribution of Type H Blood Vessels to Pathologic Osteogenesis and Inflammation in an Experimental Spondyloarthritis Model.

Kaaij MH, van Hamburg JP, van Rooijen CCN, Grüneboom A, Kan YY, Pots D, Schett G, van Ruijven LJ, van Duivenvoorde LM, Huitema LFA, Baeten DLP, Tas SW.

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Editorial: Effector functions of therapeutic antibodies.

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Cellular plasticity and myeloid inflammation in the adult brain are independent of the transcriptional modulator DREAM

Masanetz RK, Baum W, Schett G, Winkler J, Süß P.

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Disentangling tryptophan metabolism in inflammatory bowel diseases.

Becker C, Adolph TE.

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Successful Generation of CD19 Chimeric Antigen Receptor T Cells from Patients with Advanced Systemic Lupus Erythematosus

Kretschmann S, Völkl S, Reimann H, Krönke G, Schett G, Achenbach S, Lutzny-Geier G, Müller F, Mougiakakos D, Dingfelder J, Flamann C, Hanssens L, Gary R, Mackensen A, Aigner M.

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Chronic Systemic Infection of Mice with Leishmania infantum Leads to Increased Bone Mass

Lai C, Heinemann J, Schleicher U, Schett G, Bogdan C, Bozec A, Soulat D.

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Gut immune cell trafficking: inter-organ communication and immune-mediated inflammation

Guidelines for DC preparation and flow cytometry analysis of mouse lymphohematopoietic tissues

Amon L, Dudziak D, Backer RA, Clausen BE, Gmeiner C, Heger L, Jacobi L, Lehmann CHK, Probst HC, Seichter A, Tchitashvili G, Tochoedo NR, Trapaidze L, Vurnek D.

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Guidelines for DC preparation and flow cytometric analysis of human lymphohematopoietic tissues

Heger L, Dudziak D, Amon L, Hatscher L, Kaszubowski T, Lehmann CHK.

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Mechanisms and Therapeutic Modulation of Neutrophil-Mediated Inflammation

Hajishengallis G, Chavakis T.

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IL-4/IL-13-producing ILC2s are required for timely control of intestinal helminth infection in mice

Varela F, Symowski C, Pollock J, Wirtz S, Voehringer D.

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Assessment of myocardial fibrosis in patients with systemic sclerosis using [⁶⁸Ga]Ga-FAPI-04-PET-CT

Treutlein C, Distler JHW, Tascilar K, Fakhouri SC, Györfi AH, Atzinger A, Matei AE, Dees C, Büttner-Herold M, Kuwert T, Prante O, Bäuerle T, Uder M, Schett G, Schmidkonz C, Bergmann C.

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Guidelines for DC preparation and flow cytometry analysis of mouse nonlymphoid tissues

Probst HC, Stoitzner P, Amon L, Backer RA, Brand A, Chen J, Clausen BE, Dieckmann S, Dudziak D, Heger L, Hodapp K, Hornsteiner F, Hovav AH, Jacobi L, Ji X, Kamenjarin N, Lahl K, Lahmar I, Lakus J, Lehmann CHK, Ortner D, Picard M, Roberti MP, Rossnagel L, Saba Y, Schalla C, Schlitzer A, Schraml BU, Schütze K, Seichter A, Seré K, Seretis A, Sopper S, Strandt H, Sykora MM, Theobald H, Tripp CH, Zitvogel L.

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Formation and Clearance of NETs in Health and Disease

Knopf J, Mahajan A, Muñoz LE, Herrmann M.

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Hypoxia-immune-related microenvironment prognostic signature for osteosarcoma

Zhang W, Lyu P, Andreev D, Jia Y, Zhang F, Bozec A.

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Neutrophils prevent rectal bleeding in ulcerative colitis by peptidyl-arginine deiminase-4-dependent immunothrombosis

Leppkes M, Lindemann A, Gößwein S, Paulus S, Roth D, Hartung A, Liebing E, Zundler S, Gonzalez-Acera M, Patankar JV, Mascia F, Scheibe K, Hoffmann M, Uderhardt S, Schauer C, Foersch S, Neufert C, Vieth M, Schett G, Atreya R, Kühl AA, Bleich A, Becker C, Herrmann M, Neurath MF.

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Macrophages inhibit Coxiella burnetii by the ACOD1-itaconate pathway for containment of Q fever

Kohl L, Siddique MNAA, Bodendorfer B, Berger R, Preikschat A, Daniel C, Ölke M, Liebler-Tenorio E, Schulze-Luehrmann J, Mauermeir M, Yang KT, Hayek I, Szperlinski M, Andrack J, Schleicher U, Bozec A, Krönke G, Murray PJ, Wirtz S, Yamamoto M, Schatz V, Jantsch J, Oefner P, Degrandi D, Pfeffer K, Mertens-Scholz K, Rauber S, Bogdan C, Dettmer K, Lührmann A, Lang R.

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PU.1-driven Th9 Cells Promote Colorectal Cancer in Experimental Colitis Models Through Il-6 Effects in Intestinal Epithelial Cells

Gerlach K, Popp V, Wirtz S, Al-Saifi R, Gonzalez Acera M, Atreya R, Dregelies T, Vieth M, Fichtner-Feigl S, McKenzie ANJ, Rosenbauer F, Weigmann B, Neurath MF.

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Controlling in and out – the future of interfering with immune cell trafficking in inflammatory bowel disease

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A Pleomorphic Puzzle: Heterogeneous Pulmonary Vascular Occlusions in Patients with COVID-19

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Advanced neural networks for classification of MRI in psoriatic arthritis, seronegative, and seropositive rheumatoid arthritis

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Surface Design Options in Polymer- and Lipid-Based siRNA Nanoparticles Using Antibodies

Gabel M, Knauss A, Fischer D, Neurath MF, Weigmann B.

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Guidelines for mouse and human DC generation

Lutz MB, Ali S, Audiger C, Autenrieth SE, Berod L, Bigley V, Cyran L, Dalod M, Dörrie J, Dudziak D, Flórez-Grau G, Giusiano L, Godoy GJ, Heuer M, Krug AB, Lehmann CHK, Mayer CT, Naik SH, Scheu S, Schreibelt G, Segura E, Seré K, Sparwasser T, Tel J, Xu H, Zenke M.

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Biophysical phenotyping of circulating immune cells identifies a distinct monocyte-driven signature in systemic sclerosis

Matei AE, Kubánková M, Xu L, Györfi AH, Boxberger E, Soteriou D, Papava M, Prater J, Hong X, Bergmann C, Kräter M, Schett G, Guck J, Distler JHW.

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Neutrophils’ Extracellular Trap Mechanisms: From Physiology to Pathology

Schoen J, Euler M, Schauer C, Schett G, Herrmann M, Knopf J, Yaykasli KO.

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Epithelial presenilin-1 drives colorectal tumour growth by controlling EGFR-COX2 signalling

Anti-CD19 CAR T cell therapy for refractory systemic lupus erythematosus

Mackensen A, Müller F, Mougiakakos D, Böltz S, Wilhelm A, Aigner M, Völkl S, Simon D, Kleyer A, Munoz L, Kretschmann S, Kharboutli S, Gary R, Reimann H, Rösler W, Uderhardt S, Bang H, Herrmann M, Ekici AB, Buettner C, Habenicht KM, Winkler TH, Krönke G, Schett G.

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Soluble CD83 improves and accelerates wound healing by the induction of pro-resolving macrophages

Royzman D, Peckert-Maier K, Stich L, König C, Wild AB, Tauchi M, Ostalecki C, Kiesewetter F, Seyferth S, Lee G, Eming SA, Fuchs M, Kunz M, Stürmer EK, Peters EMJ, Berking C, Zinser E, Steinkasserer A.

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Intensity and longevity of SARS-CoV-2 vaccination response in patients with immune-mediated inflammatory disease: a prospective cohort study

Simon D, Tascilar K, Fagni F, Kleyer A, Krönke G, Meder C, Dietrich P, Orlemann T, Mößner J, Taubmann J, Mutlu MY, Knitza J, Kemenes S, Liphardt AM, Schönau V, Bohr D, Schuster L, Hartmann F, Minopoulou I, Leppkes M, Ramming A, Pachowsky M, Schuch F, Ronneberger M, Kleinert S, Hueber AJ, Manger K, Manger B, Atreya R, Berking C, Sticherling M, Neurath MF, Schett G.

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Toward Understanding How Staphylococcal Protein A Inhibits IgG-Mediated Phagocytosis

Cruz AR, Bentlage AEH, Blonk R, de Haas CJC, Aerts PC, Scheepmaker LM, Bouwmeester IG, Lux A, van Strijp JAG, Nimmerjahn F, van Kessel KPM, Vidarsson G, Rooijakkers SHM.

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The Memory T Cell “Communication Web” in Context with Gastrointestinal Disorders-How Memory T Cells Affect Their Surroundings and How They Are Influenced by It

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The Role of Programmed Necrosis in Colorectal Cancer

Yu YQ, Gamez-Belmonte R, Patankar JV, Liebing E, Becker C.

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Rheumatoid arthritis and osteoimmunology: The adverse impact of a deregulated immune system on bone metabolism

Phosphatidylinositol 3-Kinase (PI3K) Orchestrates Aspergillus fumigatus-Induced Eosinophil Activation Independently of Canonical Toll-Like Receptor (TLR)/C-Type-Lectin Receptor (CLR) Signaling

Dietschmann A, Schruefer S, Westermann S, Henkel F, Castiglione K, Willebrand R, Adam J, Ruland J, Lang R, Sheppard DC, Esser-von-Bieren J, Radtke D, Krappmann S, Voehringer D.

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NET Formation in Systemic Lupus Erythematosus: Changes during the COVID-19 Pandemic

Knopf J, Sjöwall J, Frodlund M, Hinkula J, Herrmann M, Sjöwall C.

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Concise report: a minimal-invasive method to retrieve and identify entheseal tissue from psoriatic arthritis patients

Pachowsky ML, Raimondo MG, Xu C, Rauber S, Tascilar K, Labinsky H, Vogg M, Aziz Saad MS, Simon D, Rech J, Soare A, Braeuer L, Kleyer A, Schett G, Ramming A.

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Targeting Human CD22/Siglec-2 with Dimeric Sialosides as Novel Oligosaccharide Mimetics

Prescher H, Schweizer A, Frank M, Kuhfeldt E, Ring J, Nitschke L.

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The soluble CD83 protein prevents bone destruction by inhibiting the formation of osteoclasts and inducing resolution of inflammation in arthritis

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Transcriptomes of MPO-Deficient Patients with Generalized Pustular Psoriasis Reveals Expansion of CD4⁺ Cytotoxic T Cells and an Involvement of the Complement System

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Induction of Ocular Surface Inflammation and Collection of Involved Tissues.

Singh J, Shan X, Mahajan A, Herrmann M, Schauer C, Knopf J, Muñoz LE.

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Rear Window-What Can the Gut Tell Us About Long-COVID?

Leppkes M, Neurath MF.

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Dynamic changes in O-GlcNAcylation regulate osteoclast differentiation and bone loss via nucleoporin 153

Li YN, Chen CW, Trinh-Minh T, Zhu H, Matei AE, Györfi AH, Kuwert F, Hubel P, Ding X, Manh CT, Xu X, Liebel C, Fedorchenko V, Liang R, Huang K, Pfannstiel J, Huang MC, Lin NY, Ramming A, Schett G, Distler JHW.

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Eosinophils, but Not Type 2 Innate Lymphoid Cells, Are the Predominant Source of Interleukin 4 during the Innate Phase of Leishmania major Infection

Sasse C, Barinberg D, Obermeyer S, Debus A, Schleicher U, Bogdan C.

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HINGEneering IgG for enhanced immune activation

Microbiota-Derived Propionate Modulates Megakaryopoiesis and Platelet Function

Dürholz K, Schmid E, Frech M, Azizov V, Otterbein N, Lucas S, Rauh M, Schett G, Bruns H, Zaiss MM.

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Angiotensin AT₂ Receptor Stimulation Alleviates Collagen-Induced Arthritis by Upregulation of Regulatory T Cell Numbers

Sehnert B, Valero-Esquitino V, Schett G, Unger T, Steckelings UM, Voll RE.

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Keratinocyte-derived S100A9 modulates neutrophil infiltration and affects psoriasis-like skin and joint disease

Mellor LF, Gago-Lopez N, Bakiri L, Schmidt FN, Busse B, Rauber S, Jimenez M, Megías D, Oterino-Soto S, Sanchez-Prieto R, Grivennikov S, Pu X, Oxford J, Ramming A, Schett G, Wagner EF.

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Efficacy and safety of SARS-CoV-2 revaccination in non-responders with immune-mediated inflammatory disease

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Transmural intestinal fibrosis in men and mice

Neufert C.

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Subjective assessment of physical function does not sufficiently explain variance of measured hand function and grip strength in arthritis patients and non-arthritis controls

Liphardt AM, Tascilar K, Coppers B, Manger E, Liehr S, Bieniek L, Bayat S, Simon D, Sticherling M, Rech J, Hueber AJ, Schett G, Kleyer A.

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Propionic acid beneficially modifies osteoporosis biomarkers in patients with multiple sclerosis

Duscha A, Hegelmaier T, Dürholz K, Desel C, Gold R, Zaiss MM, Haghikia A.

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Deciphering Pro-angiogenic Transcription Factor Profiles in Hypoxic Human Endothelial Cells by Combined Bioinformatics and in vitro Modeling

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Epithelial HIF2α expression induces intestinal barrier dysfunction and exacerbation of arthritis

Wen J, Lyu P, Stolzer I, Xu J, Gießl A, Lin Z, Andreev D, Kachler K, Song R, Meng X, Cao S, Guggino G, Ciccia F, Günther C, Schett G, Bozec A.

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Non-invasive metabolic profiling of inflammation in joints and entheses by multispectral optoacoustic tomography

Tascilar K, Fagni F, Kleyer A, Bayat S, Heidemann R, Steiger F, Krönke G, Bohr D, Ramming A, Hartmann F, Klett D, Federle A, Regensburger AP, Wagner AL, Knieling F, Neurath MF, Schett G, Waldner M, Simon D.

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Coxiella burnetii Affects HIF1α Accumulation and HIF1α Target Gene Expression

Hayek I,  Szperlinski M, Lührmann A.

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Maladaptive trained immunity and clonal hematopoiesis as potential mechanistic links between periodontitis and inflammatory comorbidities

Hajishengallis G, Li X, Divaris K, Chavakis T.

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Targeted deletion of Interleukin-3 results in asthma exacerbations

Kölle J, Zimmermann T, Kiefer A, Rieker RJ, Xepapadaki P, Zundler S, Papadopoulos NG, Finotto S.

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Effects of casirivimab/imdevimab on systemic and mucosal immunity against SARS-CoV-2 in B-cell depleted patients with autoimmune rheumatic diseases refractory to vaccination

Fagni F, Schmidt K, Bohr D, Valor-Méndez L, Hartmann F, Tascilar K, Manger K, Manger B, Kleyer A, Simon D, Schett G, Harrer T.

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Non-Invasive Characterization of Experimental Bone Metastasis in Obesity Using Multiparametric MRI and PET/CT

Gregoric G, Gaculenko A, Nagel L, Popp V, Maschauer S, Prante O, Saake M, Schett G, Uder M, Ellmann S, Bozec A, Bäuerle T.

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Maladaptive innate immune training of myelopoiesis links inflammatory comorbidities

Li X, Wang H, Yu X, Saha G, Kalafati L, Ioannidis C, Mitroulis I, Netea MG, Chavakis T, Hajishengallis G.

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IL-23 Blockade in Anti-TNF Refractory IBD: From Mechanisms to Clinical Reality

Atreya R, Neurath MF.

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Arthritis Rheumatol. 2022 May;74(5):871-881. doi: 10.1002/art.42033. Epub 2022 Mar 29.

Impaired Mitochondrial Transcription Factor A Expression Promotes Mitochondrial Damage to Drive Fibroblast Activation and Fibrosis in Systemic Sclerosis

Sequential interleukin-17/interleukin-23 inhibition in treatment-refractory psoriatic arthritis

Simon D, Fagni F, Schett G.

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Impact of Cytokine Inhibitor Therapy on the Prevalence, Seroconversion Rate, and Longevity of the Humoral Immune Response Against SARS-CoV-2 in an Unvaccinated Cohort

Simon D, Tascilar K, Kleyer A, Fagni F, Krönke G, Meder C, Dietrich P, Orlemann T, Kliem T, Mößner J, Liphardt AM, Schönau V, Bohr D, Schuster L, Hartmann F, Leppkes M, Ramming A, Pachowsky M, Schuch F, Ronneberger M, Kleinert S, Hueber AJ, Manger K, Manger B, Atreya R, Berking C, Sticherling M, Neurath MF, Schett G.

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Periodontitis-Derived Dark-NETs in Severe Covid-19

Vitkov L, Knopf J, Krunić J, Schauer C, Schoen J, Minnich B, Hannig M, Herrmann M.

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Intranasal delivery of a small-molecule ErbB inhibitor promotes recovery from acute and late-stage CNS inflammation

Linnerbauer M, Lößlein L, Vandrey O, Tsaktanis T, Beer A, Naumann UJ, Panier F, Beyer T, Nirschl L, Kuramatsu JB, Winkler J, Quintana FJ, Rothhammer V.

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SMYD2 Inhibition Downregulates TMPRSS2 and Decreases SARS-CoV-2 Infection in Human Intestinal and Airway Epithelial Cells

Yu YQ, Herrmann A, Thonn V, Cordsmeier A, Neurath MF, Ensser A, Becker C.

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Polysaccharides from European Black Elderberry Extract Enhance Dendritic Cell Mediated T Cell Immune Responses

Stich L, Plattner S, McDougall G, Austin C, Steinkasserer A.

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Alzheimer’s disease protease-containing plasma extracellular vesicles transfer to the hippocampus via the choroid plexus

Lee JH, Ostalecki C, Oberstein T, Schierer S , Zinser E, Eberhardt M Blume K, Plosnita Stich L, Bruns H, Coras R, Vera-Gonzales J, Maler M, Baur AS.

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Small but powerful: will nanoparticles be the future state-of-the-art therapy for IBD?

Lechner K, Zeeshan M, Noack M, Ali H, Neurath MF, Weigmann B.

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Higher serum levels of short-chain fatty acids are associated with non-progression to arthritis in individuals at increased risk of RA

Martinsson K, Dürholz K, Schett G, Zaiss MM, Kastbom A.

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Targeting STAT3 Signaling in COL1+ Fibroblasts Controls Colitis–Associated Cancer in Mice

Heichler C, Schmied A, Enderle K, Scheibe K, Murawska M, Schmid B, Waldner MJ, Neurath MF, Neufert C.

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Deep Learning-Based Classification of Inflammatory Arthritis by Identification of Joint Shape Patterns-How Neural Networks Can Tell Us Where to “Deep Dive” Clinically

Folle L, Simon D, Tascilar K, Krönke G, Liphardt AM, Maier A, Schett G, Kleyer A.

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Select hyperactivating NLRP3 ligands enhance the TH1- and TH17-inducing potential of human type 2 conventional dendritic cells

Heger L, Hatscher L, Lehmann CHK, Purbojo A, Onderka C, Liang C, Hartmann A, Cesnjevar R, Bruns H, Gross O, Nimmerjahn F, Ivanović-Burmazović I, Kunz M, Heger L, Dudziak D.

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Association of Structural Entheseal Lesions With an Increased Risk of Progression From Psoriasis to Psoriatic Arthritis

Simon D, Tascilar K, Kleyer A, Bayat S, Kampylafka E, Sokolova MV, Zekovic A, Hueber AJ, Rech J, Schuster L, Engel K, Sticherling M, Schett G.

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Hypoxia Promotes Neutrophil Survival After Acute Myocardial Infarction

Dölling M, Eckstein M, Singh J, Schauer C, Schoen J, Shan X, Bozec A, Knopf J, Schett G, Muñoz LE, Herrmann M.

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Inflammatory Modulation of Hematopoiesis: Linking Trained Immunity and Clonal Hematopoiesis with Chronic Disorders

Chavakis T, Wielockx B, Hajishengallis G.

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Reply to Pandey: Possible functional impact of IgG3 allotype constant region

Kallolimath S, Nimmerjahn F, Steinkellner H.

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Stromal cell regulation of inflammatory responses

Pre-incubation of corneal donor tissue with sCD83 improves graft survival via the induction of alternatively activated macrophages and tolerogenic dendritic cells

Peckert-Maier K, Schönberg A, Wild AB, Royzman D, Braun G, Stich L, Hadrian K, Tripal P, Cursiefen C, Steinkasserer A, Zinser E, Bock F.

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Siglec-F Promotes IL-33-Induced Cytokine Release from Bone Marrow-Derived Eosinophils Independently of the ITIM and ITIM-like Motif Phosphorylation

Westermann S, Dietschmann A, Doehler D, Castiglione K, Bochner BS, Voehringer D, Radtke D.

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Shigella Outer Membrane Vesicles as Promising Targets for Vaccination

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Deciphering Novel Mechanistic and Pharmacokinetic Effects of Tofacitinib in Intestinal Inflammation: Expect the Unexpected

Atreya R, Neurath MF.

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Humoral and Cellular Immune Responses to SARS–CoV–2 Infection and Vaccination in Autoimmune Disease Patients With B Cell Depletion

Simon D, Tascilar K, Schmidt K, Manger B, Weckwerth L, Sokolova M, Bucci L, Fagni F, Manger K, Schuch F, Ronneberger M, Hueber A, Steffen U, Mielenz D, Herrmann M, Harrer T, Kleyer A, Krönke G, Schett G.

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Case Report: Local Treatment of a Leishmania tropica Infection in a Syrian Child with a Novel Filmogenic Preparation of Pharmaceutical Sodium Chlorite (LeiProtect®)

Debus D, Genç S, Kurz P, Holzer M, Bauer K, Heimke-Brinck R, Baier M, Sebald H, Debus A, Bogdan C, Stahl KW.

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Tilting the Balance: Therapeutic Prospects of CD83 as a Checkpoint Molecule Controlling Resolution of Inflammation

Peckert-Maier K, Royzman D, Langguth P, Marosan A, Strack A, Sadeghi Shermeh A, Steinkasserer A, Zinser E, Wild AB.

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Apremilast inhibits inflammatory osteoclastogenesis

Degboé Y, Sunzini F, Sood S, Bozec A, Sokolova MV, Zekovic A, McInnes IB, Schett G, Goodyear CS.

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CXCR4 blockade reduces the severity of murine heart allograft rejection by plasmacytoid dendritic cell-mediated immune regulation

Giardia duodenalis and Its Secreted PPIB Trigger Inflammasome Activation and Pyroptosis in Macrophages through TLR4-Induced ROS Signaling and A20-Mediated NLRP3 Deubiquitination

Virtual teaching for medical students during SARS-CoV-2 pandemic

Neutrophils Orchestrate the Periodontal Pocket

Vitkov L, Muñoz LE, Schoen J, Knopf J, Schauer C, Minnich B, Herrmann M, Hannig M.

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There Is Strength in Numbers: Quantitation of Fc Gamma Receptors on Murine Tissue-Resident Macrophages

Vorsatz C, Friedrich N, Nimmerjahn F, Biburger M.

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Neutrophil Extracellular Traps Open the Pandora’s Box in Severe Malaria

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Soluble CD83 Inhibits T Cell Activation by Binding to the TLR4/MD-2 Complex on CD14+ Monocytes.

Rectal Delivery of a DNAzyme That Specifically Blocks the Transcription Factor GATA3 and Reduces Colitis in Mice.

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Oxidative Burst-Dependent NETosis Is Implicated in the Resolution of Necrosis-Associated Sterile Inflammation.

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Regulation of autoantibody activity by the IL-23-TH17 axis determines the onset of autoimmune disease.

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Nanoparticles size-dependently initiate self-limiting NETosis-driven inflammation.

Eur J Immunol. 2016 Sep;46(9):2121-36. doi: 10.1002/eji.201646331. Epub 2016 Jul 29.

A mutation within the SH2 domain of slp-76 regulates the tissue distribution and cytokine production of iNKT cells in mice.

New Insights into Neutrophil Extracellular Traps: Mechanisms of Formation and Role in Inflammation.

How neutrophil extracellular traps orchestrate the local immune response in gout.

Reactive oxygen homeostasis – the balance for preventing autoimmunity.

Sweet but dangerous – the role of immunoglobulin G glycosylation in autoimmunity and inflammation.

The double-edged role of 12/15-lipoxygenase during inflammation and immunity.

Siglec-H protects from virus-triggered severe systemic autoimmunity.

TNF-Mediated Restriction of Arginase 1 Expression in Myeloid Cells Triggers Type 2 NO Synthase Activity at the Site of Infection.

High fat diet increases melanoma cell growth in the bone marrow by inducing osteopontin and interleukin 6.

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CD83 Modulates B Cell Activation and Germinal Center Responses.

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Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer.

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Immune Monitoring of Trans-endothelial Transport by Kidney-Resident Macrophages.

Sci Rep. 2016 Dec 5;6:38229. doi: 10.1038/srep38229.

Blood-borne phagocytes internalize urate microaggregates and prevent intravascular NETosis by urate crystals.

Sci Transl Med. 2016 Nov 16;8(365):365ra158. doi: 10.1126/scitranslmed.aaf9418

Elucidating the interplay between IgG-Fc valency and Fc gamma R activation for the design of immune complex inhibitors.

Semin Hematol. 2016 Apr;53 Suppl 1:S10-2. doi: 10.1053/j.seminhematol.2016.04.004. Epub 2016 Apr 6.

Immunomodulation of immunothrombocytopenia.

J Clin Immunol. 2016 May;36 Suppl 1:83-7. doi: 10.1007/s10875-016-0249-6. Epub 2016 Mar 8.

Translating Inhibitory Fc Receptor Biology into Novel Therapeutic Approaches.

Cell Chem Biol. 2016 Aug 18;23(8):1014-1022. doi: 10.1016/j.chembiol.2016.07.009. Epub 2016 Aug 11.

Synthetic Lipoteichoic Acid Glycans Are Potential Vaccine Candidates to Protect from Clostridium difficile Infections.

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Oxazolone-Induced Colitis as a Model of Th2 Immune Responses in the Intestinal Mucosa.

World J Gastroenterol. 2016 Nov 14;22(42):9300-9313. doi: 10.3748/wjg.v22.i42.9300

Molecular mechanism of action of anti-tumor necrosis factor antibodies in inflammatory bowel diseases.

Mucosal Immunol. 2016 Sep;9(5):1205-17. doi: 10.1038/mi.2015.139. Epub 2016 Jan 27.

CD101 inhibits the expansion of colitogenic T cells.

Int J Med Microbiol. 2016 Aug;306(5):343-355. doi: 10.1016/j.ijmm.2016.03.004. Epub 2016 Mar 15.

Analysis of factors contributing to variation in the C57BL/6J fecal microbiota across German animal facilities

Quantification and Impact of Secondary Osteoarthritis in Patients With Anti-Citrullinated Protein Antibody-Positive Rheumatoid Arthritis.

A constant threat for HIV: Fc-engineering to enhance broadly neutralizing antibody activity for immunotherapy of the acquired immunodeficiency syndrome.

Cell Metab. 2015 Nov 3;22(5):886-94. doi: 10.1016/j.cmet.2015.08.020. Epub 2015 Sep 17.

Microbiota from Obese Mice Regulate Hematopoietic Stem Cell Differentiation by Altering the Bone Niche.

J Clin Invest. 2015 Aug 3;125(8):3297-302. doi: 10.1172/JCI79337. Epub 2015 Jul 27.

Helicobacter urease-induced activation of the TLR2/NLRP3/IL-18 axis protects against asthma.